I think the best thing about the format is that no matter what happens we have access to the vast majority of the cards (or all of them if your group is into it) and that since our decks are eternal we can just build as we go
The poster child that showcases the flexibility of modal cards is Cryptic Command
Spend that black mana to cast Gravecrawler and then sacrifice him again
This is, unfortunately, a risky gamble as there are a variety of cards that most SPYRAL builds run that can get past this including SPYRAL Gear - Big Red, Soul Charge, One for One, and Double Summon
Magic's lore involves titanic creatures including Krakens, Dragons, Dinosaurs, Eldrazi, and much more, so there's no shortage of contestants for the card with the highest toughness