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Certain skin tones and types may exhibit extreme sensitivity to vitamin C
NAC side effects are generally minimal when taken as directed, making it a safe and reliable option for long-term wellness support
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The most commonly reported adverse effects include diarrhea, nausea, abdominal cramps, and other gastrointestinal disturbances due to the osmotic effect of unabsorbed vitamin C in the gastrointestinal tract
However, another study using the CLP mouse model found that administering choline before and after sepsis initiation reduced serum inflammatory mediators such as TNF- and HMGB1, and improved survival via the 7nAChR-dependent mechanism (250, 251)
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