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References Jariwalla RJ, Lalezari J, Cenko D, Mansour SE, Kumar A, Gangapurkar B, Nakamura D
It is a clinical decision that depends on what you are trying to treat, how your body processes the peptide, and whether the product you are using is actually safe for human administration
If side effects do occur, they are generally mild and may include: Pain, discomfort, swelling, or redness at the injection site Diarrhea Headache Bloating Nausea Numbness or tingling Serious side effects are rare and may include: Confusion Dizziness or fainting Muscle pain, cramps, or weakness Extreme thirst Facial flushing Frequent urination Palpitations Fatigue Difficulty breathing Coughing or noisy breathing (wheezing) Extreme pain, swelling, warmth or tenderness in one leg Difficulty swallowing Rash Itching over the body If you experience serious side effects, contact your doctor right away
The STRIDE trial evaluated semaglutide in patients with T2DM and PAD, finding a 13% improvement in maximum walking distance and a significant increase in ankle-brachial index, indicating improved perfusion
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