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PMID 15987694

The importance of mGSH is mainly based on its detoxification of hydrogen peroxide, mitochondrial lipid membrane peroxidation, or xenobiotics under the catalysis of enzymes such as GPX or GST [58]

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Clinical relevance: Because NSV is extensive and chronic, systemic therapy is required, including topicals such as corticosteroids and calcineurin inhibitors

Quality assessment of included studies The risk of bias in the eligible included studies was assessed using the Cochrane criteria.[] The quality of all studies was assessed by two different authors (NK and BA) for following items: sequence generation, allocation sequence concealment, blinding of participants and researchers, and outcomes reporting to evaluate possible sources of bias [Figure 1]