Considering the vital role of energy requirement in the differentiation of intestinal epithelium, we extracted the differentially expressed metabolism-related genes and further examined their correlation with Satb2 expression in RNA-seq data from 43 adjacent colorectal cancer tissues in the Cancer Genome Atlas (TCGA)
Gene set enrichment analysis (GSEA) was performed with 1000 permutations to identify enriched biological functions and activated pathways from the molecular signatures database (MSigDB), which included hallmark gene sets, positional gene sets, curated gene sets, motif gene sets, computational gene sets, GO gene sets, oncogenic gene sets, and immunologic gene sets
Faster innovation leveraging Novos scale to accelerate development and access
Detoxification Glutathione plays a vital role in detoxifying the body and removing harmful substances
Obesity and Overweight (2021)