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Recent research determined that aryl hydrocarbon receptor (AhR) activation after alcohol intake in the liver, which is mediated by Protein Phosphatase 2 Regulatory Subunit-Bdelta (Ppp2r2d) to promote AMPK dephosphorylation, leading to autophagy inhibition and mitochondrial dysfunction (Kim et al., 2022)

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Research is being conducted to find a cure for the condition as well as to make current drug molecules more potent and effective by using improved formulations and delivery systems