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In addition, carrier-free nanoparticles GEM-CXB NPs formed by the nano self-assembly of the dual drugs gemcitabine and celecoxib, exhibit dual clearance of MDSCs and tumor cells thereby significantly enhancing antitumor effects by inducing ICD and alleviating MDSC-induced immunosuppression through MDSCs clearance (134)
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Lancet 384(9961):22282234
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If erythema persists beyond 72 hours or expands beyond 5 centimeters, it warrants medical evaluation
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