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Fifteen of those lost pounds were not from my GLP-1, exercise, or dietary changes but from something else entirely: skin-removal surgery
When theres sub-optimal glucose and highly active neurons have limited access to energy, they dysfunction and ultimately die on a chronic basis. The most active neurons are in regions of learning and memory, Fillit said, making them more susceptible to glucose deprivation and, ultimately, neurodegeneration
The story extends beyond biology into behavior, where the impact shows up clearly in the data
Significant weight loss from GLP-1 therapy may require levothyroxine dose adjustments, as thyroid hormone needs are partially determined by body weight
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