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In this study, we investigated the effects of dysregulated glutathione homeostasis, a principal feature of oxidative stress, on TNF-induced hepatotoxicity and its mechanistic implications in NAFLD progression
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These genes regulate each other in cycles of approximately 24 hours, and their coordinated expression is essential for proper sleep-wake rhythms
Retinol activates nuclear retinoic acid receptors and drives collagen gene transcription, but frequently causes irritation, peeling, and photosensitivity at therapeutic concentrations
Some cell-types are much less sensitive to doxorubicin-induced GSH depletion
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