A small number of people, due to specific behaviors such as fasting, vegetarianism, strenuous exercise, pregnancy, or infants fed formula not fortified with carnitine, may experience L-carnitine deficiency
N Engl J Med 381:19952008 Packer M, Anker SD, Butler J, Filippatos G, Pocock SJ, Carson P, Januzzi J, Verma S, Tsutsui H, Brueckmann M, Jamal W, Kimura K, Schnee J, Zeller C, Cotton D, Bocchi E, Bhm M, Choi DJ, Chopra V, Chuquiure E, Giannetti N, Janssens S, Zhang J, Gonzalez Juanatey JR, Kaul S, Brunner-La Rocca HP, Merkely B, Nicholls SJ, Perrone S, Pina I, Ponikowski P, Sattar N, Senni M, Seronde MF, Spinar J, Squire I, Taddei S, Wanner C, Zannad F (2020) EMPEROR-Reduced Trial Investigators
I provide education around new diabetes treatments and old diabetes treatments, to people around the world
Food and Drug Administration highlight ongoing shortages of essential neurological and CNS injectables
Although these observations are interesting, the comparison with historical control individuals is a serious limitation in the interpretation of these results