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It is certainly possible that individuals with overweight or obesity who take semaglutide may experience depressive symptoms or suicidal ideation or behavior, but the data suggest that persons not taking semaglutidein the placebo group in this studyare equally likely to experience these conditions, said Gregory Brown, PhD, a study co-author and Director of the Penn Center for the Prevention of Suicide at the Perelman School of Medicine

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While oral administration is less invasive than injection, a recent study indicated no difference in preference between oral semaglutide and dulaglutide [132]

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