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Collectively, these factors contribute to the currently higher costs of goods compared to injectable GLP-1s, reflecting additional material, process and quality complexity along the upstream value chain

By carefully designing Ipamorelin to only stimulate the release of GH, many of these unwanted side effects are avoided

Couto N, Wood J, Barber J

its safety and tolerability have not been fully clarified, and breakthroughs are still needed in production process optimization and raw material supply

It would therefore be interesting to determine if the opposite approach, i.e., simultaneously inhibiting ARC AgRP/NPY neurons and activating ARC POMC neurons, additively reduces food intake and leads to weight loss in the chronic setting as this would be therapeutically relevant