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In native endocrine systems, the release of growth hormone from anterior pituitary somatotrophs is regulated by the coordinated, simultaneous actions of endogenous GHRH and ghrelin
Many of the initial GH releasing peptides were found to significantly stimulate the release of cortisol and/or prolactin from the pituitary gland
However, regardless of the degree of involvement of the leaky gut barrier in the development of certain diseases, the persistent inflammation that accompanies damage to the intestinal barrier negatively affects the functioning of gastrointestinal tract and the whole body
Its distribution varies across tissues with uneven protection
Available at: Gokula M, Holmes HM
