Many people combine them, and if you do it wisely, it can be a strong combo
European Journal of Pharmacology, 570(1-3), 212221
Medication Adherence While medication adherence factors into outcomes associated with most all drugs, it is especially important with GLP1 receptor agonists, as significant weight gain frequently occurs after discontinuation of the drug
In-vivo(31)P-MRS of skeletal muscle and liver: a way for non-invasive assessment of their metabolism
Over time, this can lead to: Loss of lean body mass and lower resting metabolic rate Reduced protein intake , making it harder to maintain muscle Micronutrient deficiencies , particularly vitamin D, calcium, magnesium, and B-vitamins Lower energy levels and slower recovery from illness or exercise (Mozaffarian, 2025) Gastrointestinal side effects can make the picture even more complex