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Clinical trial data showed gallbladder issues in 1.4% of participants, and all cases involved people eating very low-fat diets
In many cases, insurance may cover B12 shots if medically necessary
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In particular, computational approaches, including bioinformatics and machine learning, are being used to better define sequence diversity/conservation across viruses and to aid in antigen design
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furthermore, modern sera from children were more effective at neutralizing contemporary virus, thus demonstrating the difficulty of designing a vaccine against a moving target [80]
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