In 2012, while investigating the mechanism of Erastin-induced cell death, Dixon and colleagues formally coined the term ferroptosis to describe this iron-dependent, lipid peroxidation-mediated form of regulated cell death ( Compared with other forms of cell death, such as autophagy, apoptosis, and pyroptosis, ferroptosis exhibits distinct morphological, biochemical, and immunological characteristics (Xia et al., 2025)
Increased activity of glutathione S-transferase and fast decay of reduced glutathione [PMID: 6421056] Laboratory literature summary: Increased activity of glutathione S-transferase and fast decay of reduced glutathione in Fanconi's anemia erythrocytes
focuses on developing pharmaceutical-grade glutathione products aimed at supporting liver function
For shorter periods of a few months, refrigeration at 2-8C is acceptable
135 PGC-1, which shares structural and functional similarities with PGC-1, also promotes mitochondrial biogenesis