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That conversation rules out interactions and risk factors most patients have no reason to know about

Stemmer, K., Finan, B., DiMarchi, R

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However, you should contact your healthcare provider if: Your fatigue is severe or debilitating Tiredness doesn't improve after several weeks You experience other concerning symptoms alongside fatigue You become so tired that you cannot perform daily activities These could indicate more serious issues like severe dehydration or another underlying condition that needs attention

Indeed, superoxide can undergo dismutation to H 2 O 2 , a mild oxidant that can be converted to the highly reactive hydroxyl radical in the presence of transition metals (Fe 2 + , Cu + ) by means of the Fenton reaction