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In addition to producing the antioxidant glutathione, ME-3 also produces a glutathione-containing antioxidant enzyme named glutathione peroxidase and glutathione reductase, which reactivates or recycles glutathione. As mentioned above, ME-3 is the only substance we know of to function as a complete glutathione system to synthesize, increase cellular uptake and recycle/regenerate glutathione
Consequently, therapeutic strategies have shifted toward indirect, receptor-mediated modulation
GI side effects such as nausea, vomiting, or diarrhea can also affect fluid balance
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