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Vukojevic et al., Neural Regeneration Research, 2022)

Although the precise mechanism by which these LXR agonists effect a reduction in the progression of atherosclerosis is not clear, it is known that the genes encoding ABCA1 and ABCG1 contain LXR-binding sites

Ma, S., Fan, L

However, larger and more detailed investigations are needed to assess the potential mediating effects of weight change and whether the benefits of therapy are reduced in patients with excess pancreatic fat