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De Giorgi R, Ghenciulescu A, Yotter C, Taquet M, Koychev I (2025) Glucagon-like peptide-1 receptor agonists for major neurocognitive disorders
About this article Cite this article Desai, A., Khataniar, H., Tabaku, F
Updated June 1, 2025
doi: 10.1016/j.trsl.2015.08.010 37 ZinmanBGerichJBuseJBLewinASchwartzSRaskinPet al
Richard Horowitz describes the Jarisch-Herxheimer (JH) flare as a temporary worsening of the symptoms of Lyme disease that occurs when the Lyme spirochete is being killed off by antibiotics, creating inflammationThese JH reactions produce cytokines (TNF-alpha, IL-6, and IL-8), which then create inflammatory symptoms, including increased fever, muscle and joint pain, headaches, cognitive impairment, and a general worsening of the underlying symptomology
