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Additionally, these studies continue to demonstrate that GPX4 deletion can cause oxidative damage to membranes and exacerbate neuroinflammation
Mice with a functional deletion in the modulatory subunit of the glutamatecysteine ligase ( Gclm ) display impaired glutathione synthesis leading to reduced glutathione levels in multiple organs, including the brain [80, 81]
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These difficulties are often unexpected in relation to other cognitive abilities and effective classroom instruction
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