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This medication is a compounded drug product that has not been reviewed or approved by the FDA for safety, effectiveness, or quality

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It does not leach chemicals into the solution

That said, ZMA contains moderate-to-high doses of the individual nutrients zinc, magnesium, and vitamin B6, which may cause side effects, such as ( Zinc: nausea, vomiting, loss of appetite, stomach cramps, diarrhea, and headaches