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The damage induced by hyperglycemia was generally regarded as results from a series of chain reactions triggered by inflammatory responses, leading to increased activity of the transcription factor NF-B
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Given the reciprocal relationship between AMPK and mTOR signalling 36 and the links between mTOR and PGC1 signalling 37 , we next explored the role of mTOR
All participants were administered an identical intervention (1cm 3 of saline containing 200 mg GSH) using a syringe attached to a Mucosal Atomization Device supplied by Wolfe-Tory Medical (Salt Lake City, UT, USA)
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