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The use of compounds that stimulate Sirtuin and AMPK modulators SIRT1/SIRT6 (e.g., resveratrol, NMN) has shown potential to restore mitochondrial biogenesis and attenuate OS in insulin-resistant tissues (Wang et al., 2023), although robust clinical trials are lacking
Yuan et al., 2017)
A 2023 paper in Acta Biomaterialia investigated photo-crosslinkable hyaluronic-acid-based hydrogel embedded with GHK-peptide nanofibers as a delivery vehicle for skin-applications (PMID 37832839)
GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine
Its primary job is to stimulate the production of collagen and elastinthe proteins that give your skin its structure and bounce
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