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doi: 10.1016/S0140-6736(10)60590-9 41 WangWNevrezLFilippovaESongKHTaoBGuLet al

Its Phase 2 obesity program did not meet the primary weight-loss endpoint, development was discontinued, and the compound is not FDA-approved or TGA-approved for any indication

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This reduces TNF- production, decreases IL-6 secretion, and lowers overall inflammatory cytokine expression

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