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A contribution of NTS astrocytes to the appetite suppression caused by acute GLP-1R agonists also seems possible from evidence showing (1) expression of GLP-1Rs in this cell type, (2) functional responses of astrocytes to exendin-4 and liraglutide, and (3) negation of appetite suppression from administration of exendin-4 into the NTS when astrocyte metabolism is selectively inhibited in this region [56]
10.1073/pnas.0504423102 170 WangJ
With BPC-157, the available literature points more toward a response-modulating profile that appears under specific stress, injury, vascular, or repair-associated conditions
Science 304 , 700703 (2004)
When to Check In With Your Doctor 8 Ways to Fight Back Against GLP-1 Fatigue 1
