Together, they aim to introduce new products tailored to individual patient needs, showing the industry's focus on targeted treatment approaches
doi: 10.1172/JCI68295 74 AthaudaDMaclaganKSkeneSSBajwa-JosephMLetchfordDChowdhuryKet al
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As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively
Data sources included publicly available summary-level data from GWAS studies as well as expression quantitative trait loci (eQTL) data