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Taken together, these guidelines reinforce SGLT2i as the backbone of CKD management across diabetic and non-diabetic disease, with GLP-1 RAs positioned as additive therapy for appropriately selected patients, rather than as replacements
doi:10.2337/dc22-2300 Silverii GA, Monami M, Gallo M, Ragni A, Prattichizzo F, Renzelli V, et al
in a large heterogeneous population agents with varying impacts on obesity-related conditions, on weight loss response, on side effect profile, on route of administration, all have the potential for wide use.
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