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The plasma concentrations of 51 Cr-EDTA are then measured in a gamma counter, with the log [ 51 Cr-EDTA] against time used to determine the GFR [17]
The mTORC1 inhibition by AMPK is accomplished by direct phosphorylation of the regulatory-associated protein of mTOR (Raptor) [264] and indirectly via activation of TSC2 [265, 266]
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