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In women with PCOS, high concentrations of leptin have been reported to inhibit the expression of aromatase mRNA in granulosa cells, while the hyperandrogenic follicular environment in GCs was found to significantly reduce the expression of P450arom, which can convert androgens into estrogen, further increasing the levels of androgens and ultimately promoting follicular atresia (148150)
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Based on our review of the available research, doses of 1-2 mg per day of reconstituted injectable GHK-Cu offer numerous therapeutic benefits in test subjects including anti-inflammatory action, tissue repair, hair growth, and more
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