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Thus, the potent IRAP inhibitor 45 demonstrated for ERAP1 an IC50 of 43 nM and for ERAP2 an IC50 value of 37 nM

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Korean J Physiol Pharmacol (2014) 18(5):397402.10.4196/kjpp.2014.18.5.397 63 KimJ-SRyuS-YYunIKimW-JLeeK-SParkJ-Wet al1alpha,25-Dihydroxyvitamin D(3) protects dopaminergic neurons in rodent models of Parkinsons disease through inhibition of microglial activation

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