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Plant-derived bioactive substances, including polyphenols (flavonoids, phenolic acids, anthocyanins), polysaccharides (inulin, fructooligosaccharides, plant polysaccharides), saponins (ginsenosides, astragaloside IV), and alkaloids (berberine), have been shown to possess multiple biological activities such as gut microbiota modulation, intestinal barrier improvement, reduction of inflammatory factor release, and antioxidant effects ( Probiotics and prebiotics, as nutritional intervention approaches for gut microbiota modulation, have shown promising application prospects in DKD management
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