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Box 1: Practical consultation tips for administration of rectal formulations Example advice given to patients for administration of suppositories: You might find it easier to use a suppository before bed to minimise any leakage
The initiation dose is always given intravenously at around 6mg/kg, thereafter it is switched to a SC formulation at 90mg 12-weekly or 8-weekly[95]
This matters practically
For example, Vitamin B12 injections are often given every 1-2 weeks, while other vitamins may be administered less frequently
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