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Briefly, berberine plays a neuroprotective effect by promoting autophagy clearance and reducing A production ( Besides, it is indicating that berberine facilitates nerve regeneration via JNK-AKT signal pathway mediated by insulin-like growth factor receptor (Zhang H

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A control tripeptide (L-glutamyl-L-histidyl-L-proline) was inactive in the same system, indicating that the effect is sequence- and copper-coordination-specific rather than a general copper-delivery phenomenon

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