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FOXO4-DRI at 25 mM concentration selectively induced p53 nuclear exclusion and apoptosis in the senescent Leydig cells, confirmed by Annexin V-FITC/PI apoptosis assays and immunofluorescent staining of Ser15-phospho-p53 foci
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Tag modification could potentially interfere with proteinprotein interactions and subsequent pulldown assays 19
Tranexamic acid stops plasmin from activating, which lowers inflammation and stops hyperpigmentation from happening
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