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Effect of glutathione on Bd In vitro, Bd zoosporangia responded to low levels of exogenous glutathione via a dramatic and sustained increase in zoospore production

129 Stabilized -catenin translocates to the nucleus and partners with TCF/LEF transcription factors to activate oncogenic targets, including MYC, Cyclin D1, LGR5, CD44, and ABCB1, genes that regulate proliferation, drug efflux, and stemness

Third, we compile emerging therapeutic strategies not comprehensively addressed in earlier reviews, including structure-based -syn aggregation inhibitors (e.g., SP1, 4,554 W), glia-targeting nanoformulations, LRRK2 kinase inhibitors in clinical translation, and non-pharmacological interventions such as physical exerciseall contextualized within the -synferroptosis axis

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