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extremely short half-life (~13 minutes)

Obesity Medicine Director, Mercy Weight Loss Surgery Program, Bakersfield, California

While all of the mechanisms by which GLP-1 agonists assist with weight loss are not yet fully understood, below are the well-established ways in which these injectable medications can contribute to weight loss: GLP-1s slow the release of glucagon and stimulate the secretion of insulin, thereby keeping blood sugar low

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It also means the drowsiness effect will hit you during your waking hours, which most patients find disruptive