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These lifestyle changes dont replace medication, but they make it work better
Compared to newer GLP-1s, Victoza leads to modest A1C lowering and weight loss
However, baseline ASCVD or HF showed a statistically significant impact on MACE ( P = 0.0195, I 2 = 0.00%, R 2 = 100%), indicating that these comorbidities fully accounted for the variability in MACE events, while metformin use had a modest effect
By targeting metabolic dysfunction while addressing inflammatory pathways, GLP-1s offer a means of treating HS within a broader context of multimorbidity rather than as an isolated cutaneous condition
Study designs often include safety/tolerability panels, adverseevent monitoring (e.g., GIrelated events), and lab chemistry trends over time
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