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On the one hand, a 2020 pilot study showed that increased growth hormone circulation could preserve quadriceps strength in patients whod undergone reconstructive surgery after an anterior cruciate ligament injury;18 on the other, an in vitro study from 2024 found that growth hormone administered to tendon and ligament cells [did] not appear to positively affect cellular proliferation and differentiation.19 More research is needed before we can say for sure whether CJC-1295, ipamorelin, and similar peptide treatments have dependable utility toward injury recovery
Active treatment increased brachial artery diameter by 2.3% (P=.008), consistent with reduced arterial tone
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It was developed to stimulate the release of growth hormone (GH) from the pituitary gland without significantly affecting cortisol or prolactin levels
This triple mechanism distinguishes it from existing agents such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GIP/GLP-1 agonist)
