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Their main sites of action are white and brown adipose tissue, and muscle
The primary endpoint of weight loss of at least 5% occurred in 85% of the tirzepatide 5 mg group, 89% of the tirzepatide 10 mg group and 91% of participants in the tirzepatide 15 mg group
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Intriguingly, observational studies demonstrate that patients with a higher BMI may have more severe psoriasis, and weight loss has been associated with improvements in PASI scores in patients treated with biological agents
The researchers commented that the peptide appears to possess the behavioral, pharmacological, and neuroanatomical specificity required to potentially influence sexual function
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