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J Thorac Dis 15(7):3522-3524, 2023
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Patients with suspected SLE should be referred urgently to Secondary Care (if renal involvement refer to nephrology, otherwise rheumatology or dermatology) Systemic steroids are required, sometimes at a high-dose, to manage flares, and most patients require a low-dose as maintenance Antimalarials may have a role in those with marked photosensitivity Immunosuppressive drugs may be required as steroid sparing agents Cyclophosphamide can be useful for renal disease Prognosis - the course of SLE is highly variable
Khi bn ng su, c th bc vo qu trnh sa cha v ti to t bo
The Nrf2 (nuclear factor erythroid 2-related factor 2)Keap1 (Kelch-like ECH-associated protein 1)ARE (antioxidant response element) signaling pathway is a master regulator of cellular defense against oxidative and electrophilic stress
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