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In contrast, its intestinal microbial metabolite, urolithin, possesses better biological activity and higher bioavailability [173]

By promoting the KLF15/Nrf2 signaling pathway, sirtuin7 (Sirt7) attenuated renal ferroptosis, lipid peroxidation, and epithelial mesenchymal transition (EMT) in the hypertensive state, thereby attenuating renal fibrosis [160]

While all cells can synthesize glutathione for use within the cell, the liver also produces glutathione in larger amounts and exports it into the plasma and bile

Insufficient sleep increases glutathione degradation