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The same phenomenon was observed in the aortic tissues of aging mice after FOXO4-DRI treatment (Figures 6C,D)
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However, the NAC monotherapy arm (600 mg three times daily) showed a trend toward slower decline in forced vital capacity (FVC) that did not reach statistical significance compared to placebo (Martinez et al., N Engl J Med, 2014) [45]
(BNP reference ranges) Hubbard RE, O'Mahony MS, Woodhouse KW
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