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In contrast, the passive diffusion process of B 12 absorption normally a very small portion of total absorption of the vitamin from food consumption may exceed the haptocorrin- and IF-mediated absorption when oral doses of B 12 are very large, with roughly 1% efficiency
& Diebold, Y
This effect is mediated by a reduction in the synthesis of prostaglandins, which are cell-signaling molecules derived from the omega-6 fatty acid arachidonic acid via the action of the cyclooxygenase enzymes (Downie 1991
Dipeptidyl peptidase-4 inhibitors and gallbladder or biliary disease in type 2 diabetes: systematic review and meta-analysis (BMJ)
doi: 10.2174/138161211796196954
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