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Current nanoparticle formulations (such as lipid nanoparticles, nanoemulsion, metal complexes, etc.) have significantly improved the stability, targeted delivery efficiency, and local concentration of curcumin through encapsulation technology, among them, lipid carriers (such as SLNSNLCS) have become a research hotspot due to their high Biocompatibility and controlled release properties, nanoemulsion enhances skin penetration due to the advantage of small particle size, and functionalized metal nanoparticles can synergize antioxidant and photoprotection

Tumors and major organs including heart, liver, spleen, lung, and kidney were isolated