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Poll -/- Polm -/- MEFs and PolX -/- MEFs were grown in media additionally supplemented with 5 mM N-acetyl-L-cysteine (Sigma)
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(9) an alternative mechanism of action of FB1 involves the disruption of the de novo sphingolipid biosynthesis pathway by inhibition of the enzyme ceramide synthase [68, 112]
Moharir SC, Sirohi K, Swarup G
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