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Huis group discovered a specific combination of three transcription factors consisting of GATA4, HNF1 and FOXA3, which converted p19 Arf/ mouse tail-tip fibroblasts to iHeps with a higher conversion efficiency ( Hnf1a and Foxa3 transduction was already sufficient to induce iHeps and addition of Gata4 enhanced the conversion efficiency ( Hnf1 and Foxa3 directly induced MEFs into hepatic stem cells which had the bipotential of differentiating into hepatocytes and cholangiocytes (Yu et al., 2013)
Osteoarthritis burden and inequality from 1990 to 2021: a systematic analysis for the global burden of disease Study 2021
I tapered myself down from the dosage my doctor gave me because I hated not having any appetite whatsoever, plus I wanted to deal with fewer lows, Brennan agreed
J Neuroinflammation 8:21
Another MRI study suggested it reduces tongue fat deposition, which correlates with changes in weight and waist circumference
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