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More recently, the SUMMIT trial demonstrated that tirzepatide reduced the composite risk of cardiovascular death or worsening heart failure by 38% (HR = 0.62, 95% CI: 0.410.95) in patients with heart failure with preserved ejection fraction (HFpEF) and a BMI 30 kg/m 2 , 32% of whom also had type 2 diabetes
M., Crowley, D
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While their choices may help to inform the decision-making of plan sponsors in other industries, ultimately all employers will need to weigh the clinical and financial issues to ensure their benefit design reflects their philosophy, program objectives and fiscal reality.
Some pilot studies reported symptomatic improvement, but large randomized controlled trials have not yet confirmed disease-modifying effects
