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Digestive/GI side effects are common: nausea, vomiting, diarrhea, constipation, delayed gastric emptying (gastroparesis) have all been documented
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At the bottom of a titration schedule this becomes untenable a 0.25 mg step is 2.5 units , which is not reliably measurable on a standard U-100 syringe with 1- or 2-unit graduations
Lalwani N
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Additional studies by Ma et al
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