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10.1097/01.ta.0000087648.01543.9f 31 HuangT.ZhangK.SunL.XueX.ZhangC.ShuZ.et al (2015)
Peptides Containing Glutamine or Asparagine These amino acids are susceptible to deamidation
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Important safety considerations include the risk of hypoglycemia when tirzepatide is used in combination with insulin or sulfonylureas (requiring dose adjustments of these medications), potential thyroid C-cell tumor risk (contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), and the possibility of acute pancreatitis
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